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The fact is that, as the science fiction writer Norman Spinrad says, "psychochemistry [has] created states of consciousness
that had never existed before."
Taking a psychedelic dramatically changes the traditional notionsof "free will." Spinrad's view is that "psycho-chemicals are a declaration of independence from the minds wewere born with," and that hence "we will no longer be able to count on our 'naturally evolved' brain chemistryas a benchmark of sanity."

Peter Stafford Citation

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